Just out, Better the drug you know: commentary on Daughton 2020, Natural Experiment Concept to Accelerate the Re-purposing of Existing Therapeutics for Covid-19 https://www.sciencedirect.com/science/article/pii/S2590113320300110

Broadbent A. 2020. Better the drug you know: commentary on Daughton 2020, Natural Experiment Concept to Accelerate the Re-purposing of Existing Therapeutics for Covid-19. Global Epidemiology 2(10027):1-2. https://doi.org/10.1016/j.gloepi.2020.100027

This is a (positive) commentary on what I thought was a really useful idea for accelerating research into anti-COVID drugs, which I shared previously and which you can (and should) read here:

Daughton CG. 2020. Natural experiment concept to accelerate the re-purposing of existingtherapeutics for Covid-19. Global Epidemiology 2(100026):1–6.66. https://doi.org/10.1016/j.gloepi.2020.100026

And the author Christian Daughton posted a reply to my commentary here:

Daughton CG. 2020. Response to: Broadbent 2020, Better the drug you know: Commentary on “Daughton 2020, Natural experiment concept to accelerate the re-purposing of existing therapeutics for Covid-19”. Global Epidemiology 2(100028):1-2. https://doi.org/10.1016/j.gloepi.2020.100028

 

“the truth is that lockdown is a luxury, and it’s a luxury that the middle classes are enjoying and higher income countries are enjoying at the expense of the poor, the vulnerable and less developed countries” Sunetra Gupta @FreddieSayers @unherd

https://unherd.com/2020/05/oxford-doubles-down-sunetra-gupta-interview/

Loads of great points

  • COVID on the way out in UK
  • Antibody tests unreliable, don’t show prevalence
  • Infections rates shouldn’t even be reported; dependent on testing
  • R number depends on immunity and thus a red herring
  • Everywhere same curve: up, then gently down (resonant of Michael Levitt’s interview in the same place). Immunity explains better than a load of different explanations for all the countries with different measures.
  • And lockdown is retrogressive, not progressive; it’s dumb to bundle up the anti-lockdown people as on the right (or left I guess). It’s a luxury that the rich can afford and the poor can’t.

This Thursday at 11:30am (via Zoom) the @CHESS_DurhamUni reading group will be discussing our recent report from the IFK, ‘A Framework for Decisions in a Post-COVID World’ by @AlexBroadbent

This Thursday at 11:30am (via Zoom) the @CHESS_DurhamUni reading group will be discussing ‘A Framework for Decisions in a Post-COVID World‘ by @AlexBroadbent . . . please contact admin.chess@durham.ac.uk for the paper and joining instructions #COVID19 #socialpolicy #policymakers

Video now up – the first in our series of webinars, Reimagining the world after COVID-19, with Joyce Banda, Johan Giesecke and Sehaam Khan

This event took place on Wednesday 13 May 2020.

 

A simple and FAST method for identifying existing drugs that may work against COVID-19 has just been published: https://www.sciencedirect.com/science/article/pii/S2590113320300109 This deserves to be widely read and tried. #epitwitter

Daughton CG. Natural experiment concept to accelerate the Re-purposing of existing therapeutics for Covid-19. Global Epidemiology 2:1-6.

I’ve got a commentary coming out soon too.

 

“Two months later, it has not been the worst-case scenario many envisioned,” says the New York Times (strongly pro-lockdown, as a rule). In other words: what critics of Sweden said two months ago was entirely wrong.

nyti.ms/2ZcFmmm

Let’s see whether the Swedes continue to be right, about the advantages of their strategy over a longer time frame.

Chief of Health at UNICEF Stefan Peterson @stefanswartpet tells @Telegraph what he told us weeks ago: that the lockdown will kill children and most likely more people than it saves

https://www.telegraph.co.uk/global-health/science-and-disease/unicef-warns-lockdown-could-kill-covid-19-model-predicts-12/

It’s important to bear in mind that the appropriate comparison is not lockdown-or-bust, but lockdown vs. some more moderate and contextually feasible social distancing measures in conjunction with protection of vulnerable groups.

The documentary where he told us this to us is below.

7 minute low-res version:

 

30 minute high res version: